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KMID : 0032220220340060412
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Annals of Dermatology
2022 Volume.34 No. 6 p.412 ~ p.418
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Efficacy and Safety of Cold-Induced Noninvasive Targeted Fat Reduction in Pseudogynecomastia
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Hong Ji-Yeon
Park Su-Jung
Kim Soo-Yeon
Kim Beom-Joon
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Abstract
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Background : Treatment options for pseudogynecomastia are limited, and the demand for noninvasive breast fat reduction is increasing.
Objective :We evaluated the efficacy and safety of a cold-induced lipolysis device for treating pseudogynecomastia.
Methods : In this 16-week prospective trial, a total of 15 male patients with pseudogynecomastia were treated twice with cryolipolysis. The primary endpoint was a change in the chest circumference from baseline at posttreatment week 8. Secondary endpoints were changes in body weight, fat thickness assessed using ultrasonography, independent evaluator- and patient-rated improvement, and Simon’s gynecomastia class (SGC) grading.
Results : The primary assessment, a reduction of 3.05 cm in the mean chest circumference at 8 weeks post-treatment compared to baseline, was statistically significant. The treatment effect was cumulative, with a steady decrease in chest circumference and fat thickness over the 16-week study period. The mean pain score immediately after the first session of treatment was 2.0±1.36, based on a scale of 0~10, with a score of 10 being the worst pain ever experienced. The pain decreased substantially after the end of the procedure.
Conclusion : Cryolipolysis was demonstrated to be an effective and safe option for reducing breast fat in pseudogynecomastia. Male with mild to moderate breast enlargement without skin excess can be ideal candidates.
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KEYWORD
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Adipose tissue, Diet therapy, Gynecomastia
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